Extending the excitation wavelength from UV to visible light for a europium complex-based mitochondria targetable luminescent probe for singlet oxygen

Hua Ma; Xin Wang; Bo Song; Liu Wang; Zhixin Tang; Tianlie Luo; Jingli Yuan

doi:10.1039/c8dt02829j

Extending the excitation wavelength from UV to visible light for a europium complex-based mitochondria targetable luminescent probe for singlet oxygen

Dalton Trans. 2018 Oct 7;47(37):12852-12857. doi: 10.1039/c8dt02829j. Epub 2018 Aug 28.

Authors

Hua Ma¹, Xin Wang¹, Bo Song¹, Liu Wang², Zhixin Tang¹, Tianlie Luo³, Jingli Yuan¹

Affiliations

¹ State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Linggong Road 2, Dalian 116024, China. bo.song@dlut.edu.cn.
² School of Pharmaceutical Science and Technology, Dalian University of Technology, Linggong Road 2, Dalian 116024, China.
³ Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, Dalian University of Technology, Linggong Road 2, Dalian 116024, China.

PMID: 30151539
DOI: 10.1039/c8dt02829j

Abstract

A visible-light-excitable Eu³⁺ complex-based luminescent probe, [Eu(pdap)₃(DPBT)], has been proposed for time-gated luminescence imaging of singlet oxygen in the mitochondria of living cells, as well as in tumor tissues and laboratory animals. Extension of the excitation window to the visible-light region makes the probe more favorable for practical usage.