Ovarian Teratoma or Uterine Malformation? PET/MRI as a Novel Useful Tool in NMDAR Encephalitis

In Vivo. 2018 Sep-Oct;32(5):1231-1233. doi: 10.21873/invivo.11369.

Abstract

This is a case report of a 17-year-old girl affected by N-methyl-D-aspartate-receptor (NMDAR) encephalitis suspected for a paraneoplastic syndrome. Ultrasound (US) and computed tomography (CT) imaging identified an ovarian lesion compatible with teratoma. 18F-fluorodeoxyglucose (FDG) positron emission tomography/magnetic resonance imaging (PET/MRI), performed to evaluate metabolic activity of the brain and of the ovarian mass, correctly changed the diagnosis to uterine malformation that was later histologically proven.

Keywords: NMDAR; PET/MRI; encephalitis; ovarian teratoma; uterine malformation.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / blood
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / diagnosis*
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis / genetics
  • Diagnosis, Differential
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Magnetic Resonance Imaging*
  • Ovarian Neoplasms / diagnosis*
  • Positron-Emission Tomography*
  • Teratoma / diagnosis*
  • Tomography, X-Ray Computed
  • Urogenital Abnormalities / diagnosis*
  • Uterus / abnormalities*

Substances

  • Fluorodeoxyglucose F18

Supplementary concepts

  • Teratoma, Ovarian
  • Uterine Anomalies