Chitosan⁻Carboxymethylcellulose-Based Polyelectrolyte Complexation and Microcapsule Shell Formulation

Jagadish Chandra Roy; Ada Ferri; Stéphane Giraud; Guan Jinping; Fabien Salaün

doi:10.3390/ijms19092521

Chitosan⁻Carboxymethylcellulose-Based Polyelectrolyte Complexation and Microcapsule Shell Formulation

Int J Mol Sci. 2018 Aug 25;19(9):2521. doi: 10.3390/ijms19092521.

Authors

Jagadish Chandra Roy^{1

2

3

4}, Ada Ferri⁵, Stéphane Giraud^{6

7}, Guan Jinping⁸, Fabien Salaün^{9

10}

Affiliations

¹ Departments of Applied Science and Technology, Politecnico di Torino, 10129 Torino, Italy. jagadish.roy@polito.it.
² Department of Mechanical, Energy and Material Engineering, University of Lille Nord de France, F-5900 Lille, France. jagadish.roy@polito.it.
³ Department of Textile Material Engineering, École Nationale Supérieure des Arts et Industries Textiles, 59056 Roubaix, France. jagadish.roy@polito.it.
⁴ College of Textile and Clothing Engineering, Soochow University, Suzhou 215000, China. jagadish.roy@polito.it.
⁵ Departments of Applied Science and Technology, Politecnico di Torino, 10129 Torino, Italy. ada.ferri@polito.it.
⁶ Department of Mechanical, Energy and Material Engineering, University of Lille Nord de France, F-5900 Lille, France. stephane.giraud@ensait.fr.
⁷ Department of Textile Material Engineering, École Nationale Supérieure des Arts et Industries Textiles, 59056 Roubaix, France. stephane.giraud@ensait.fr.
⁸ College of Textile and Clothing Engineering, Soochow University, Suzhou 215000, China. guanjinping@suda.edu.cn.
⁹ Department of Mechanical, Energy and Material Engineering, University of Lille Nord de France, F-5900 Lille, France. fabien.salaun@ensait.fr.
¹⁰ Department of Textile Material Engineering, École Nationale Supérieure des Arts et Industries Textiles, 59056 Roubaix, France. fabien.salaun@ensait.fr.

Abstract

Chitosan (CH)⁻carboxymethyl cellulose sodium salt (NaCMC) microcapsules containing paraffin oil were synthesized by complex formation, and crosslinked with glutaraldehyde (GTA). The electrostatic deposition of NaCMC onto the CH-coated paraffin oil emulsion droplets was demonstrated by zeta potential and optical microscopy. The optimal process conditions were identified in terms of pH of the aqueous solution (5.5) and CH/NaCMC mass ratio (1:1). Encapsulation of paraffin oil and microcapsule morphology were analyzed by ATR-FTIR and SEM, respectively. The effect of GTA crosslinking on paraffin oil latent heat was investigated by DSC and combined with the values of encapsulation efficiency and core content, supporting the compact shell formation.

Keywords: carboxymethyl cellulose sodium salt; chitosan; emulsion; microcapsule; polyelectrolyte complex.

MeSH terms

Capsules
Carboxymethylcellulose Sodium / chemistry*
Chitosan / chemistry*
Drug Compounding*
Emulsions
Hydrogen-Ion Concentration
Polyelectrolytes / chemistry*
Polyelectrolytes / pharmacology
Solutions
Spectroscopy, Fourier Transform Infrared
Thermodynamics

Substances

Capsules
Emulsions
Polyelectrolytes
Solutions
Chitosan
Carboxymethylcellulose Sodium