Data-Driven Assessment of Potentially Inappropriate Medication in the Elderly

Stud Health Technol Inform. 2018:253:125-129.

Abstract

Multimorbid patients taking polypharmacy represent a growing population at high risk for inappropriate prescribing. Various lists for identifying potentially inappropriate medication are spread across scientific journals and difficult to access. To address this ongoing need, a new database named PIMBase is developed which integrates these well-known lists and unifies their rating scales. The analysis of the pharmacovigilance data reveals the benefits of combining the lists. PIMBase is meant to be a web-based system and starting point for the data-driven assessment of polypharmacy to identify inappropriate medication and to improve the quality of prescribing. PIMBase is available at https://pimbase.kalis-amts.de.

Keywords: Drug-Related side effects and adverse reactions; computer-assisted decision making; decision support systems; inappropriate prescribing; information systems; medication errors; polypharmacy; potentially inappropriate medication list.

MeSH terms

  • Aged
  • Drug-Related Side Effects and Adverse Reactions
  • Humans
  • Inappropriate Prescribing
  • Internet*
  • Pharmacovigilance*
  • Polypharmacy*
  • Potentially Inappropriate Medication List*
  • Statistics as Topic