Primary Cardiac Lymphoma: A Lesson Learned from an Unsuccessful Experience

Intern Med. 2018 Dec 15;57(24):3569-3574. doi: 10.2169/internalmedicine.0594-17. Epub 2018 Aug 24.

Abstract

A 79-year-old man was admitted because of complete heart block. Echocardiograms showed an abnormal mass adjacent to the sinus of Valsalva. Subsequent surgical resection was not successful. Despite chemotherapy, the patient died from multiple organ failure. It is important to recognize that approximately 80% of cases of cardiac lymphoma are diffuse large B-cell lymphoma, which is the only malignant neoplasm that may respond well to chemotherapy with rituximab. In order to save patients' lives, the early implementation of chemotherapy with rituximab is critical and should be considered as a therapeutic diagnostic option in select patients.

Keywords: early implementation of treatment; primary cardiac lymphoma; rituximab; therapeutic diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Agents, Immunological / therapeutic use
  • Biopsy
  • Echocardiography
  • Heart Atria
  • Heart Neoplasms / diagnosis*
  • Heart Neoplasms / drug therapy
  • Humans
  • Lymphoma, Large B-Cell, Diffuse / diagnosis*
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Male
  • Rituximab / therapeutic use*
  • Tomography, X-Ray Computed

Substances

  • Antineoplastic Agents, Immunological
  • Rituximab