Staff and ambient radiation dose resulting from therapeutic nuclear medicine procedures

Appl Radiat Isot. 2018 Nov:141:270-274. doi: 10.1016/j.apradiso.2018.07.014. Epub 2018 Jul 12.

Abstract

With associated cure rates in excess of 90%, targeted 131I radioactive iodine therapy has clearly improved thyroid cancer survival. Thus said, potential radiation risks to staff represent a particular concern, current study seeking to determine the radiation exposure of staff from 131I patients during hospitalization, also estimating accumulated dose and related risk to staff during preparation of the radioactive iodine. In present study made over the three-month period 1st February to 1st May 2017, a total of 69 patient treatments were investigated (comprising a cohort of 46 females and 23 males), this being a patient treatment load typically reflective of the workload at the particular centre for such treatments. The patients were administered sodium iodide 131I, retained in capsules containing activities ranging from 370 to 5550 MBq at the time of calibration, radioiodine activity depends on many factors such as gender, clinical indication, body mass index and age. The staff radiation dose arising from each patient treatment was measured on three consecutive days subsequent to capsule administration. In units of µSv, the mean and dose-rates range at distances from the patients of 5 cm, 1 m and 2 m were 209 ± 73 (165-294), 6.8 ± 2 (5.3-9.5) and 0.9 ± 0.3 (0.7-1.2). The annual dose (also measured in units of µSv), based on annual records of doses, for medical physicists, technologists and nurses were 604, 680 and 1000 µSv respectively. In regard to current practice and workload, staff exposures were all found to be below the annual dose limit for radiation workers.

Keywords: Occupational exposure; Radiation dosimetry; Radiation risk; Radioiodine; Therapeutic NM.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Humans
  • Iodine Radioisotopes / adverse effects*
  • Male
  • Middle Aged
  • Occupational Exposure / adverse effects*
  • Radiation Dosage
  • Radiation Exposure / adverse effects*
  • Radiation Monitoring / instrumentation
  • Radiopharmaceuticals / adverse effects*
  • Thyroid Neoplasms / radiotherapy
  • Young Adult

Substances

  • Iodine Radioisotopes
  • Iodine-131
  • Radiopharmaceuticals