Neurodevelopmental Outcomes of Preterm Children at School Age and Beyond

Anne Synnes; Matthew Hicks

doi:10.1016/j.clp.2018.05.002

Neurodevelopmental Outcomes of Preterm Children at School Age and Beyond

Clin Perinatol. 2018 Sep;45(3):393-408. doi: 10.1016/j.clp.2018.05.002.

Authors

Anne Synnes¹, Matthew Hicks²

Affiliations

¹ Neonatal Follow-Up Program, British Columbia's Women's Hospital, University of British Columbia, Room 1R16, 4500 Oak Street, Vancouver, British Columbia V6H 3N1, Canada. Electronic address: asynnes@cw.bc.ca.
² Department of Pediatrics, Neonatal Intensive Care Unit, University of Alberta, 5027 Diagnosis and Treatment Centre, Royal Alexander Hospital, 10240 Kingsway Northwest, Edmonton, Alberta T5H 3V9, Canada.

PMID: 30144845
DOI: 10.1016/j.clp.2018.05.002

Abstract

Despite improved survival of preterm infants, there has not been an equivalent improvement in long-term neurodevelopmental outcomes. Adverse neurodevelopmental outcome rates and severity are inversely related to the degree of prematurity, but only 1.6% are born very preterm and the motor, cognitive, behavioral, and psychiatric disabilities in the large moderate and late preterm population have a greater impact. The disability-free preterm adult has a lower educational achievement and income but similar health-related quality of life to term controls. Reducing the long-term neurodevelopmental impact of prematurity is the next frontier of neonatal care.

Keywords: Child development; Cognitive; Developmental disabilities; Follow-up; Motor; Neuro development; Outcomes; Preterm.

Publication types

Review

MeSH terms

Adolescent
Cerebral Palsy / epidemiology*
Cerebral Palsy / physiopathology
Child
Cognitive Dysfunction / epidemiology*
Cognitive Dysfunction / physiopathology
Developmental Disabilities / epidemiology*
Developmental Disabilities / physiopathology
Educational Status*
Gestational Age
Hearing Loss / epidemiology*
Hearing Loss / physiopathology
Humans
Infant, Extremely Premature
Infant, Newborn
Infant, Premature
Intelligence
Language Development Disorders / epidemiology*
Language Development Disorders / physiopathology
Mental Health*
Motor Skills Disorders / epidemiology*
Motor Skills Disorders / physiopathology
Neurodevelopmental Disorders / epidemiology
Neurodevelopmental Disorders / physiopathology
Patient Reported Outcome Measures
Quality of Life
Risk-Taking
Vision Disorders / epidemiology*
Vision Disorders / physiopathology