Acute genital ulcers: keep Lipschütz ulcer in mind

Arch Gynecol Obstet. 2018 Nov;298(5):927-931. doi: 10.1007/s00404-018-4866-6. Epub 2018 Aug 24.

Abstract

Aim: Lipschütz ulcers (LU) were first described as rare vulvar ulcerations that affect adolescents without previous history of sexual contact. However, more LU patients have been identified in acute genital ulcers (AGU) services in Europe.

Purpose: To review cases of AGU and analyze the occurrence of LU in the Ob/Gyn Emergency Department of a Brazilian private hospital, using the currently used diagnostic criteria.

Methods: All female patients who sought our service with AGU complaints from January 2009 to July 2015 were selected and had their medical records reviewed, considering the clinical data and some diagnostic criteria, that included: < 20 years old, first AGU episode, sudden onset, absence of sexual contact 3 months before onset and the absence of immunodeficiency.

Results: 273 patients eligible for analysis were identified according to the criteria and 12 (4.39%) of them were identified with the possible diagnosis of LU. By applying less restrictive criteria that allowed the inclusion of patients of any age and sexual status, 98 were identified (35.89%).

Conclusions: Despite being described as a rare pathology, ours and previous results indicate a considerable number of AGU cases, suggesting that LU should be better known and considered for differential diagnosis.

Keywords: Acute genital ulcer; Acute vulvar ulcer; Lipschütz ulcer; Ulcus vulvae acutum; Vulvar disease.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brazil
  • Child
  • Databases, Genetic
  • Diagnosis, Differential
  • Europe
  • Female
  • Herpes Genitalis / complications
  • Herpes Genitalis / diagnosis
  • Humans
  • Middle Aged
  • Ulcer / diagnosis*
  • Ulcer / pathology
  • Ulcer / virology
  • Vulvar Diseases / diagnosis*
  • Vulvar Diseases / pathology
  • Vulvar Diseases / virology
  • Young Adult