Could combinations of new and old drugs enhance tumor cell death?

João Ma Delou; Karina L Hajdu; Helena L Borges

doi:10.2217/fon-2018-0339

Could combinations of new and old drugs enhance tumor cell death?

Future Oncol. 2018 Oct;14(23):2319-2322. doi: 10.2217/fon-2018-0339. Epub 2018 Aug 24.

Authors

João Ma Delou¹, Karina L Hajdu¹, Helena L Borges¹

Affiliation

¹ Biomedical Sciences Institute, Federal University of Rio de Janeiro, Rio de Janeiro, 21949-590, Brazil.

PMID: 30139272
DOI: 10.2217/fon-2018-0339

No abstract available

Keywords: anticancer chemotherapy; antineoplastic agents; cell cycle; cell death; chemotherapy; clinical trials; cyclin-dependent kinases; drug combinations; drug development; polypharmacology.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Autophagy / drug effects
Cell Death / drug effects
Clinical Trials as Topic
Humans
Neoplasms / diagnosis
Neoplasms / drug therapy*
Neoplasms / metabolism
Treatment Outcome