[Progress in repair and reconstruction of large segmental bone tumor defect in distal tibia]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2018 Sep 15;32(9):1211-1217. doi: 10.7507/1002-1892.201803007.
[Article in Chinese]

Abstract

Objective: To review the methods of repair and reconstruction of the large segmental bone tumor defect in distal tibia.

Methods: The related literature of repair and reconstruction of the large segmental bone tumor defect in disatal tibia were reviewed and analyzed from the aspects of the reserved ankle joint and the non-reserved ankle joint.

Results: The large segmental bone tumor defect in distak tibia is not rare in clinical. In addition to conventional allograft bone transplantation, vascularized autologous fibular transplantation, vascularized fibular allograft, inactivated tumor regeneration, distraction osteogenesis, and bone transport techniques; membrane-induced osteogenesis, artificial tumor stem prosthesis, three-dimensional printed metal trabecular prosthesis, ankle arthrodesis, artificial tumor ankle joint placement surgery are now gradually applied to the repair and reconstruction of large segmental bone defects in the distal tibia. Moreover, due to its long survival time, the function of reconstruction of the bone tumor defect in the distal tibia has also received increasing attention.

Conclusion: Although the ideal methods of repair and reconstruction of the large segmental bone tumor defect in the distal tibia has not yet been developed, great progress has been achieved. Recently, with the appearance of three-dimensional printing and various preoperative simulation techniques, personalized and precise therapy could become ture, but therapies for the large segmental bone tumor defect in the distal tibia still need to be further explored.

目的: 对胫骨下段大段瘤性骨缺损的修复重建方式进行综述。.

方法: 查阅国内外胫骨下段大段瘤性骨缺损重建方式的相关文献,从保留踝关节及非保留踝关节等方面进行总结分析。.

结果: 胫骨下段大段瘤性骨缺损在临床上并不少见,除了常规的同种异体骨移植、带血管自体腓骨移植、同种异体骨复合带血管的腓骨移植、瘤段灭活回植、牵张成骨及骨搬运技术外,膜诱导成骨技术、人工肿瘤干假体、3D 打印金属骨小梁假体、踝关节融合术、人工肿瘤踝关节置换术目前也开始逐渐应用于胫骨下段大段瘤性骨缺损的修复重建。另外,因胫骨下段恶性肿瘤患者生存期较长,对胫骨下段大段瘤性骨缺损修复重建后的功能也得到越来越多关注。.

结论: 胫骨下段大段瘤性骨缺损修复重建的最佳方式仍存在争议,但也获得长足进步。而且随着近年来 3D 打印技术及各类术前模拟技术的出现,使个性化、精准化治疗成为可能,但对于胫骨下段大段瘤性骨缺损的修复重建仍需继续探讨。.

Keywords: Distal tibia; large segmental bone tumor defect; repair and reconstruction.

MeSH terms

  • Ankle Joint
  • Arthrodesis
  • Bone Neoplasms*
  • Bone Transplantation
  • Fibula
  • Humans
  • Osteogenesis, Distraction
  • Prostheses and Implants
  • Tarsal Bones
  • Tibia
  • Transplantation, Autologous

Grants and funding

国家重点研发计划资助项目(2016YFC1102003);四川省科技研究项目(2017SZ0095)