Feasibility of correlation mapping optical coherence tomography angiographic technique using a 200 kHz vertical-cavity surface-emitting laser source for in vivo microcirculation imaging applications

Appl Opt. 2018 Aug 1;57(22):E224-E231. doi: 10.1364/AO.57.00E224.

Abstract

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and functional parameters such as oxygen saturation. In this study, we present a modified scanning-based correlation mapping OCT using a 200 kHz high-speed swept-source OCT system operating at 1300 nm and demonstrate its wide field-imaging capability in ocular angiographic studies.

MeSH terms

  • Feasibility Studies
  • Fluorescein Angiography / methods*
  • Humans
  • Microcirculation / physiology*
  • Optic Disk / blood supply*
  • Phantoms, Imaging
  • Retinal Vessels / diagnostic imaging*
  • Retinal Vessels / physiology
  • Tomography, Optical Coherence / methods*