Curvature-driven spatial patterns in growing 3D domains: A mechanochemical model for phyllotaxis

PLoS One. 2018 Aug 16;13(8):e0201746. doi: 10.1371/journal.pone.0201746. eCollection 2018.

Abstract

Here we discuss the formation of phyllotactic patterns in the shoot apical meristem (SAM) of plants, where the spatial distribution of the phytohormone auxin determines phyllotaxis in a domain that is growing and changing in time. We assume that the concentration of auxin modifies the mechanical properties of the domain and that the mechanical stress field in the SAM orients the flux of auxin. To study this problem we propose a mechanism for pattern formation in growing domains with variable curvature. The dynamics of chemicals is modeled by a reaction-diffusion system that produces a three dimensional pattern of chemical concentrations that changes the stress field in the domain while growing. The growth process is modeled by a phase-field order parameter which determines the location of the boundaries of the domain. This field is coupled to the chemical concentration through a curvature term that affects the local mechanical stress in the domain. The local stress changes in turn modify the chemical patterns. Our model constitutes a useful and novel approach in theoretical biology, as many developmental processes in organisms seem to be affected by the changes of curvature, size, mechanical stress and other physical aspects. Several patterns seen in many plants are reproduced under certain conditions by our model.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomechanical Phenomena
  • Chemotaxis
  • Computer Simulation
  • Diffusion
  • Indoleacetic Acids / metabolism*
  • Meristem / growth & development*
  • Meristem / metabolism
  • Models, Biological*
  • Plant Development*
  • Plant Leaves / anatomy & histology
  • Plant Leaves / growth & development*
  • Plant Leaves / metabolism
  • Plant Shoots / anatomy & histology
  • Plant Shoots / growth & development*
  • Plant Shoots / metabolism
  • Plants / anatomy & histology
  • Plants / metabolism
  • Stress, Mechanical

Substances

  • Indoleacetic Acids

Grants and funding

This work was supported by Dirección General de Asuntos del Personal Académico, Universidad Nacional Autonoma de Mexico (MX); PAPIIT-IN110817; PASPA; dgapa.unam.mx (JLA) 2, and Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México, DGAPA (PASPA) UNAM for a sabbatical grant, RAB. Mara D Rueda-Contreras is a doctoral student from Programa de Doctorado en Ciencias Biomédicas in Instituto de Neurobiología at Universidad Nacional Autónoma de México, and received fellowship 371688 from Consejo Nacional de Ciencia y Tecnología. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.