The field of object detection has made great progress in recent years. Most of these improvements are derived from using a more sophisticated convolutional neural network. However, in the case of humans, the attention mechanism, global structure information, and local details of objects all play an important role for detecting an object. In this paper, we propose a novel fully convolutional network, named as Attention CoupleNet, to incorporate the attention-related information and global and local information of objects to improve the detection performance. Specifically, we first design a cascade attention structure to perceive the global scene of the image and generate class-agnostic attention maps. Then the attention maps are encoded into the network to acquire object-aware features. Next, we propose a unique fully convolutional coupling structure to couple global structure and local parts of the object to further formulate a discriminative feature representation. To fully explore the global and local properties, we also design different coupling strategies and normalization ways to make full use of the complementary advantages between the global and local information. Extensive experiments demonstrate the effectiveness of our approach. We achieve state-of-the-art results on all three challenging data sets, i.e., a mAP of 85.7% on VOC07, 84.3% on VOC12, and 35.4% on COCO. Codes are publicly available at https://github.com/tshizys/CoupleNet.