Composite chronic myeloid leukemia and essential thrombocythemia with BCR-ABL1 fusion and CALR mutation

Am J Hematol. 2019 Apr;94(4):504-505. doi: 10.1002/ajh.25249. Epub 2018 Sep 21.

Authors

Daniel Xia^{1

2}, Eric D Hsi³, Paola Dal Cin⁴, Robert P Hasserjian¹

Affiliations

¹ Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.
² Department of Pathology, University Health Network, Toronto, Ontario.
³ Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
⁴ Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.

PMID: 30105753
DOI: 10.1002/ajh.25249

No abstract available

Publication types

Case Reports

MeSH terms

Aged
Calreticulin* / genetics
Calreticulin* / metabolism
Female
Fusion Proteins, bcr-abl* / genetics
Fusion Proteins, bcr-abl* / metabolism
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / metabolism
Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / pathology
Mutation*
Thrombocythemia, Essential* / genetics
Thrombocythemia, Essential* / metabolism
Thrombocythemia, Essential* / pathology

Substances

BCR-ABL1 fusion protein, human
CALR protein, human
Calreticulin
Fusion Proteins, bcr-abl