Organic Bioelectronics: Materials and Biocompatibility

Int J Mol Sci. 2018 Aug 13;19(8):2382. doi: 10.3390/ijms19082382.

Abstract

Organic electronic materials have been considered for a wide-range of technological applications. More recently these organic (semi)conductors (encompassing both conducting and semi-conducting organic electronic materials) have received increasing attention as materials for bioelectronic applications. Biological tissues typically comprise soft, elastic, carbon-based macromolecules and polymers, and communication in these biological systems is usually mediated via mixed electronic and ionic conduction. In contrast to hard inorganic semiconductors, whose primary charge carriers are electrons and holes, organic (semi)conductors uniquely match the mechanical and conduction properties of biotic tissue. Here, we review the biocompatibility of organic electronic materials and their implementation in bioelectronic applications.

Keywords: biocompatibility; bioelectronics; drug delivery; nerve cell regeneration; neural interface; organic electronics.

Publication types

  • Review

MeSH terms

  • Animals
  • Biocompatible Materials / chemistry*
  • Biocompatible Materials / pharmacology
  • Biosensing Techniques
  • Cell Adhesion / drug effects
  • Drug Carriers / chemistry
  • Humans
  • Polymers / chemistry
  • Semiconductors*

Substances

  • Biocompatible Materials
  • Drug Carriers
  • Polymers