Sensors for Fetal Hypoxia and Metabolic Acidosis: A Review

Sensors (Basel). 2018 Aug 13;18(8):2648. doi: 10.3390/s18082648.

Abstract

This article reviews existing clinical practices and sensor research undertaken to monitor fetal well-being during labour. Current clinical practices that include fetal heart rate monitoring and fetal scalp blood sampling are shown to be either inadequate or time-consuming. Monitoring of lactate in blood is identified as a potential alternative for intrapartum fetal monitoring due to its ability to distinguish between different types of acidosis. A literature review from a medical and technical perspective is presented to identify the current advancements in the field of lactate sensors for this application. It is concluded that a less invasive and a more continuous monitoring device is required to fulfill the clinical needs of intrapartum fetal monitoring. Potential specifications for such a system are also presented in this paper.

Keywords: electrochemical sensing; fetal blood sampling; fetal monitoring; hypoxia; lactate; lactate hydrogenase; lactate oxidase; obstetrics; optical sensing.

Publication types

  • Review

MeSH terms

  • Acidosis / diagnosis*
  • Female
  • Fetal Hypoxia / diagnosis*
  • Fetal Monitoring / instrumentation*
  • Humans
  • Labor, Obstetric*
  • Lactic Acid / blood
  • Pregnancy
  • Scalp

Substances

  • Lactic Acid