Facial Involvement in Dermatitis Herpetiformis: A Case Report and Review of the Literature

J Cutan Med Surg. 2019 Jan/Feb;23(1):35-37. doi: 10.1177/1203475418795818. Epub 2018 Aug 13.

Abstract

Dermatitis herpetiformis is a cutaneous manifestation of celiac disease that classically presents as a symmetric pruritic vesicular eruption on extensor surfaces. Typical locations include elbows, knees, and buttocks. Facial involvement has been reported rarely. Here, we report a case of a 44-year-old woman with dermatitis herpetiformis presenting as pruritic vesicles on the face that had previously been misdiagnosed as allergic contact dermatitis. Diagnosis was confirmed with direct immunofluorescence demonstrating granular IgA in the papillary dermis. This eruption cleared with topical dapsone 5% gel and a gluten-free diet. We report this case to raise awareness of facial involvement in dermatitis herpetiformis as well as the possibility of topical dapsone as a therapeutic option.

Keywords: celiac disease; dapsone; dermatitis herpetiformis; face; gluten free diet.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Celiac Disease / complications
  • Celiac Disease / diagnosis
  • Celiac Disease / diet therapy
  • Dermatitis Herpetiformis* / diagnosis
  • Dermatitis Herpetiformis* / etiology
  • Diet, Gluten-Free
  • Female
  • Forehead / pathology*
  • Humans
  • Male
  • Middle Aged
  • Skin / pathology*