Objective: Introduction: Stability of the chemical composition of the body is one of the most important and mandatory conditions for its normal functioning. Accordingly, deviations in the content of chemical elements caused by environmental, climatic-geographical factors or diseases will lead to a wide range of disorders in the state of health. Therefore, the identification and evaluation of deviations in the exchange of macro- and microelements, as well as their correction, are a promising direction of modern medicine. The aim of the work is to reveal the regularity of distribution of diselementoses and the elemental profile of pathology in women from various regions of the Republic of Sakha (Yakutia).
Patients and methods: Materials and methods: Using the multielement analysis system using AES-ISP and MS-ISP methods, the content of chemical elements in the hair of 555 women from various regions of the Republic of Sakha (Yakutia) was investigated. The study of hair was conducted on the content of 24 chemical elements (Al, As, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, P, Pb, Se, Si, Sn, Ti, V, Zn , μg / g).
Results: Results and conclusions: The results obtained show that the risk of hyperelementosis in the female population of the Republic of Sakha (Yakutia) is significantly increasing in the direction of south-south; in the direction of north-south the risk of development of hypo-elemental diseases increases significantly. At the same time, the central regions of the republic are an exception to the general scheme: the prevalence of excessive accumulation in the hair as toxic and essential chemical elements is also great here, as in the arctic regions of the republic.
Keywords: North; Yakutia; ecology; health; microelements.