Updates on Transcranial Magnetic Stimulation Therapy for Major Depressive Disorder

Psychiatr Clin North Am. 2018 Sep;41(3):419-431. doi: 10.1016/j.psc.2018.04.006.

Abstract

Transcranial magnetic stimulation has emerged as a treatment option for treatment-resistant depression. While existing data largely support efficacy of transcranial magnetic stimulation for major depressive disorder, ongoing research aims to optimize treatment parameters and identify biomarkers of treatment response. In this article, the authors describe data from controlled trials and ongoing efforts to enhance transcranial magnetic stimulation outcomes for major depressive disorder. Findings from preliminary research aimed at identifying neuroimaging and neurophysiological biomarkers of transcranial magnetic stimulation effects are discussed.

Keywords: Depression; Noninvasive neuromodulation; Transcranial magnetic stimulation; Treatment-resistant depression.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Brain / diagnostic imaging
  • Brain / physiopathology*
  • Depressive Disorder, Major / diagnostic imaging
  • Depressive Disorder, Major / physiopathology
  • Depressive Disorder, Major / therapy*
  • Depressive Disorder, Treatment-Resistant / diagnostic imaging
  • Depressive Disorder, Treatment-Resistant / physiopathology
  • Depressive Disorder, Treatment-Resistant / therapy*
  • Electroencephalography / methods*
  • Humans
  • Nerve Net / diagnostic imaging
  • Nerve Net / physiopathology*
  • Neuroimaging / methods*
  • Transcranial Magnetic Stimulation / methods*
  • Transcranial Magnetic Stimulation / standards