Influence of process parameters on microcapsule formation from chitosan-Type B gelatin complex coacervates

Jagadish Chandra Roy; Stéphane Giraud; Ada Ferri; Raffaella Mossotti; Jingpin Guan; Fabien Salaün

doi:10.1016/j.carbpol.2018.06.087

Influence of process parameters on microcapsule formation from chitosan-Type B gelatin complex coacervates

Carbohydr Polym. 2018 Oct 15:198:281-293. doi: 10.1016/j.carbpol.2018.06.087. Epub 2018 Jun 21.

Authors

Jagadish Chandra Roy¹, Stéphane Giraud², Ada Ferri³, Raffaella Mossotti⁴, Jingpin Guan⁵, Fabien Salaün²

Affiliations

¹ University Lille Nord de France, F-5900 Lille, France; ENSAIT, GEMTEX, 2 allée Louise et Victor Champier - BP 30329 - 59056 Roubaix cedex 1, France; Departments of Applied Science and Technology, Politecnico di Torino, Torino, Italy; College of Textile and Clothing Engineering, Soochow University, Suzhou, Jiangsu, China. Electronic address: jagadish-chandra.roy@ensait.fr.
² University Lille Nord de France, F-5900 Lille, France; ENSAIT, GEMTEX, 2 allée Louise et Victor Champier - BP 30329 - 59056 Roubaix cedex 1, France.
³ Departments of Applied Science and Technology, Politecnico di Torino, Torino, Italy.
⁴ CNR-ISMAC, Institute for Macromolecular Studies, Corso G. Pella 16, 13900 Biella, Italy.
⁵ College of Textile and Clothing Engineering, Soochow University, Suzhou, Jiangsu, China.

PMID: 30093001
DOI: 10.1016/j.carbpol.2018.06.087

Abstract

A series of chitosan/gelatin based microcapsules containing n-hexadecane was synthesized through complex phase coacervation from chitosan (CH) and type-B gelatin (GB), and crosslinked by glutaraldehyde (GTA). This research was conducted to clarify the influence of different parameters on the encapsulation process, i.e., the emulsion formation and the shell formation, using zeta potential and surface tension measurements, attenuated total reflectance (ATR), and thermal analysis such as differential scanning calorimetry (DSC). The optimal values of biopolymer ratios (TBP), crosslinker amount, emulsion time and feeding weight ratio of core/shell polymer (RCS) were identified. The stability of the emulsion was depended on the surface activity and TBP ratio, which also affected the droplet size distribution and the thickness of the shell. Furthermore, core content, encapsulation efficiency and thermal properties of the microcapsules were related to TBP and RCS; with the lowest RCS giving the best microcapsules features.

Keywords: Chitosan; Complex coacervation; Microcapsules; Shell; Type B gelatin.