We present a rare case report of a patient diagnosed with primary plasma cell leukemia (PCL) who presented with atypical signs and symptoms which acutely evolved into life-threatening multi-organ failure. This case raises questions regarding the latest diagnostic guidelines and therapeutic options in the management of acute PCL and reinforces the need for prompt treatment after diagnosis.
Keywords: Atypical symptoms; multi-organ failure; multiple myeloma; plasma cell leukemia; primary plasma cell leukemia; prompt diagnosis; targeted therapy.