Keeping Parents Apart

Arunika Das; Michael A Lampson

doi:10.1016/j.devcel.2018.07.019

Keeping Parents Apart

Dev Cell. 2018 Aug 6;46(3):255-256. doi: 10.1016/j.devcel.2018.07.019.

Authors

Arunika Das¹, Michael A Lampson²

Affiliations

¹ Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
² Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: lampson@sas.upenn.edu.

PMID: 30086299
DOI: 10.1016/j.devcel.2018.07.019

Abstract

Parental genomes are initially separate in the zygote following fertilization. A recent study in Science by Reichmann et al. (2018) reveals that dual spindles assemble around the two pronuclei in mouse embryos to maintain separation of the two parental genomes through the first zygotic division.

Publication types

Comment

MeSH terms

Animals
Cell Nucleus*
Fertilization
Genome
Mice
Zygote*

Grants and funding

R01 HD058730/HD/NICHD NIH HHS/United States