RNAi Doxxes Segregation Distorters on the X

Justin P Blumenstiel; Colin D Meiklejohn

doi:10.1016/j.devcel.2018.07.013

RNAi Doxxes Segregation Distorters on the X

Dev Cell. 2018 Aug 6;46(3):251-253. doi: 10.1016/j.devcel.2018.07.013.

Authors

Justin P Blumenstiel¹, Colin D Meiklejohn²

Affiliations

¹ Department of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045, USA. Electronic address: jblumens@ku.edu.
² School of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA. Electronic address: cmeiklejohn2@unl.edu.

PMID: 30086297
DOI: 10.1016/j.devcel.2018.07.013

Abstract

Species with chromosomal sex determination are susceptible to an evolutionary tug-of-war over sex chromosome segregation. RNA silencing has been proposed to play a role in this intragenomic conflict. Reporting in Developmental Cell, Lin et al. (2018) demonstrate that RNA interference is key to this conflict as a genome defender.

Publication types

Comment

MeSH terms

Biological Evolution
Chromosome Segregation*
RNA Interference*