Intraventricular haemorrhage as the first manifestation of congenital Cytomegalovirus infection

Indian J Med Microbiol. 2018 Apr-Jun;36(2):279-281. doi: 10.4103/ijmm.IJMM_18_11.

Abstract

Congenital Cytomegalovirus infection (CCMV) is the most common intrauterine infection. Early diagnosis of CCMV is hindered by three factors: There is no screening programme for CMV infection in pregnant women; a high percentage of infections in neonates are asymptomatic; the clinical signs of CCMV infection are uncharacteristic. The aim of this article is to analyse the clinical picture and course of CCMV treatment in a 3-week-old newborn, analyse adverse events in 14-week-long antiviral therapy and also assess intraventricular bleeding as an early indicator for the diagnosis of CCMV.

Keywords: Congenital Cytomegalovirus infection; intraventricular haemorrhage; lenticulostriate vasculopathy.

Publication types

  • Case Reports

MeSH terms

  • Basal Ganglia Cerebrovascular Disease / diagnosis
  • Basal Ganglia Cerebrovascular Disease / etiology
  • Congenital Abnormalities / diagnosis
  • Congenital Abnormalities / etiology
  • Cytomegalovirus / pathogenicity
  • Cytomegalovirus Infections / complications*
  • DNA, Viral / genetics
  • Female
  • Humans
  • Infant, Newborn
  • Pregnancy

Substances

  • DNA, Viral