N,N-Dimethylformamide and N,N-dimethylacetamide are multipurpose reagents which deliver their own H, C, N and O atoms for the synthesis of a variety of compounds under a number of different experimental conditions. The review mainly highlights the corresponding literature published over the last years.
Keywords: DMAc; DMF; N,N-dimethylacetamide; N,N-dimethylformamide; amidation; amination; carbonylation; cyanation; cyclization; formylation; insertion; thioamidation.