Recent Uses of N, N-Dimethylformamide and N, N-Dimethylacetamide as Reagents

Molecules. 2018 Aug 3;23(8):1939. doi: 10.3390/molecules23081939.

Abstract

N,N-Dimethylformamide and N,N-dimethylacetamide are multipurpose reagents which deliver their own H, C, N and O atoms for the synthesis of a variety of compounds under a number of different experimental conditions. The review mainly highlights the corresponding literature published over the last years.

Keywords: DMAc; DMF; N,N-dimethylacetamide; N,N-dimethylformamide; amidation; amination; carbonylation; cyanation; cyclization; formylation; insertion; thioamidation.

Publication types

  • Review

MeSH terms

  • Acetamides / chemistry*
  • Dimethylformamide / chemistry*
  • Indicators and Reagents / chemistry*
  • Molecular Structure
  • Organic Chemicals / chemical synthesis*
  • Solvents / chemistry*

Substances

  • Acetamides
  • Indicators and Reagents
  • Organic Chemicals
  • Solvents
  • Dimethylformamide
  • dimethylacetamide