Chemotherapy is one of the effective methods to treat cancer. However, the chemotherapy agents may cause a series of adverse reactions due to the nonselective characteristics that affect not only tumor cells, but also normal cells. Oral mucositis induced by chemotherapy is a common oral complication caused by chemotherapy in clinic. It brings great suffering to the patients and also interferes with the procedure of chemotherapy. Because of its high incidence in patients receiving chemotherapy and the significant influence, there are more researches on oral mucositis induced by chemotherapy which let us have further understanding of it. This review article will introduce the pathogenesis, risk factors, clinical manifestations, assessments, treatment and prevention of oral mucositis induced by chemotherapy.
化疗是目前治疗癌症最有效的手段之一，但由于目前的化疗药物缺乏选择性，既能作用于肿瘤细胞，也能作用于正常细胞，因此造成了一系列的不良反应。化疗性口炎是一种临床上常见的由化疗导致的口腔并发症，它不仅给患者带来极大痛苦，甚至有可能影响患者化疗的顺利进行。由于化疗性口炎在接受化疗的患者中发生率较高且影响重大，因此目前关于化疗性口炎的研究逐渐增加，也使临床医师对化疗性口炎有了进一步认识。本文从发病机制、危险因素、临床表现、评估标准、治疗及预防等方面对化疗性口炎进行综述。.
Keywords: Antineoplastic combined chemotherapy protocols; Oral mucositis; Prevention; Treatment.