Hepatitis E Virus: A New Foodborne Zoonotic Concern

Adv Food Nutr Res. 2018:86:55-70. doi: 10.1016/bs.afnr.2018.04.002. Epub 2018 May 21.

Abstract

Hepatitis E virus (HEV) is an enteric nonenveloped single-stranded RNA virus. Among the mammalian lineages, four genotypes are associated to human infection: genogroups 1 and 2 infect only humans and are mainly found in developing countries, while genogroups 3 and 4 are zoonotic, being found in a variety of animal species including pigs, and are autochthonous in developed countries. HEV infection can result in liver damage and with genotypes 1 and 2 symptoms can be particularly severe in pregnant women, with a high lethality ratio. Several cases of foodborne transmission of hepatitis E have been reported, often involving consumption of meat, especially raw or undercooked. Information is lacking on the exact extent of foodborne transmission of HEV.

Keywords: Food safety; Hepatitis E; Hepatitis E virus; Pork products; Zoonosis.

Publication types

  • Review

MeSH terms

  • Animals
  • Foodborne Diseases / virology*
  • Global Health
  • Hepatitis E / epidemiology
  • Hepatitis E / pathology
  • Hepatitis E / virology*
  • Hepatitis E virus / genetics
  • Hepatitis E virus / physiology*
  • Humans
  • Zoonoses*