Direct In Vivo Microbial Transcriptomics During Infection

Abstract

The challenge in infectious diseases is monitoring infection in the host. Omics-based genomics and transcriptomics can define microbial genes expressed during infection and treatment with antimicrobials. Recent studies pinpoint a direct in situ in vivo approach revolutionizing infection monitoring and optimizing antimicrobial therapy using machine learning.

Keywords: Pseudomonas aeruginosa; in vitro comparisons; in vivo transcription; microbial infections.