Investigation of the hemodynamics of a juxtarenal aortic aneurysm with intervention by dual-stents strategy

Abstract

Objective: To study the feasibility of using two stents (a combination of multilayer stent [MS] and stent graft [SG]) in the treatment of a juxtarenal aortic aneurysm that involves a significant branch artery and to determine the advantages and disadvantages of using SGs upstream and downstream from the aneurysm so as to provide some theoretical guidance for preoperative clinical decision-making in the future.

Methods: Four ideal geometric models were established for numerical computation: case 1 refers to an aneurysm without the use of stents, case 2 represents the implantation of two MSs in an aneurysm, and case 3 (SG + MS) and case 4 (MS + SG) both involve the treatment of an aneurysm by using a combination of SG and MG.

Results: The aneurysm pressure is slightly lower and there are more vortices when the SG is implanted (case 3 and case 4). In particular, for case 4, additional vortices appear in the sac and the area of the low-wall shear stress is larger on the aneurysm compared with those of the other three cases. However, the pressure becomes uneven, and a peak pressure region is observed on the wall of the aneurysm, and therefore, the aneurysmal wall will become buckled. In addition, the flux of the renal artery in the four cases is greater than that in the normal case.

Conclusion: The arrangements in cases 3 and 4 can effectively isolate the aneurysm from circulation, but clinically, it is necessary to avoid such a high-risk situation wherein the SG is positioned downstream of the aneurysm (case 4), even though this leads to improved isolation.

Keywords: Branch artery; Hemodynamics; Juxtarenal aortic aneurysm; Multilayer stent; Stent graft.