Acute kidney injury associated with hypercalcaemic crisis in a patient with primary hyperparathyroidism

BMJ Case Rep. 2018 Jul 30:2018:bcr2018225235. doi: 10.1136/bcr-2018-225235.

Abstract

Parathyroid or hypercalcaemic crisis is a rare presenting manifestation of primary hyperparathyroidism and usually seen in relation to parathyroid carcinoma and multiple myeloma. We present a middle-aged woman with extreme hypercalcaemia due to parathyroid adenoma presenting as acute kidney injury. This case highlights the need to consider primary hyperparathyroidism in differentials of a patient presenting with severe hypercalcaemia and renal dysfunction. Also this is the second reported case in literature of a patient surviving such extreme hypercalcaemia due to parathyroid adenoma.

Keywords: acute renal failure; calcium and bone; endocrine system; renal system.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / etiology*
  • Acute Kidney Injury / therapy
  • Female
  • Humans
  • Hypercalcemia / diagnosis*
  • Hypercalcemia / etiology
  • Hypercalcemia / surgery
  • Hyperparathyroidism, Primary / diagnosis*
  • Hyperparathyroidism, Primary / metabolism
  • Hyperparathyroidism, Primary / physiopathology
  • Middle Aged
  • Parathyroid Glands / pathology*
  • Parathyroid Neoplasms / diagnosis*
  • Parathyroid Neoplasms / physiopathology
  • Parathyroid Neoplasms / surgery
  • Parathyroidectomy*
  • Radionuclide Imaging
  • Treatment Outcome