Antioxidant properties of ferrous flavanol mixtures

Michalina Grzesik; Grzegorz Bartosz; Andrzej Dziedzic; Dorota Narog; Jacek Namiesnik; Izabela Sadowska-Bartosz

doi:10.1016/j.foodchem.2018.06.076

Antioxidant properties of ferrous flavanol mixtures

Food Chem. 2018 Dec 1:268:567-576. doi: 10.1016/j.foodchem.2018.06.076. Epub 2018 Jun 19.

Authors

Michalina Grzesik¹, Grzegorz Bartosz², Andrzej Dziedzic³, Dorota Narog⁴, Jacek Namiesnik⁵, Izabela Sadowska-Bartosz⁶

Affiliations

¹ Department of Analytical Biochemistry, Faculty of Biology and Agriculture, University of Rzeszów, Zelwerowicza Street 4, 35-601 Rzeszów, Poland.
² Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Łódź, Pomorska Street 141/143, 90-236 Łódź, Poland.
³ Center of Innovation & Knowledge Transfer, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland.
⁴ Faculty of Chemistry, Rzeszów University of Technology, P. O. Box 85, 35-959 Rzeszów, Poland.
⁵ Department of Analytical Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Narutowicza Street 11/12, 80-233 Gdańsk, Poland.
⁶ Department of Analytical Biochemistry, Faculty of Biology and Agriculture, University of Rzeszów, Zelwerowicza Street 4, 35-601 Rzeszów, Poland. Electronic address: isadowska@poczta.fm.

PMID: 30064798
DOI: 10.1016/j.foodchem.2018.06.076

Abstract

Interaction of metal, especially iron ions with flavanols is considered as an important feature of these compounds and is believed to contribute to their both antioxidant and prooxidant properties. The aim of this study was to examine how Fe²⁺ binding to form a 4:1 (flavanol:Fe²⁺) mixtures affects the antioxidant properties of flavanols. ABTS^∗ scavenging, protection against fluorescence bleaching induced by AAPH and hypochlorite, protection against lipid peroxidation and protection against hypochlorite-induced hemolysis demonstrated that flavonol-Fe²⁺ mixtures retain antioxidant properties, although, in most cases, they are lower with respect to the flavanols alone. No superoxide dismutase-like or catalase-like activity of the mixtures was revealed.

Keywords: (+)-Catechin, CID: 9064; (−)-Epicatechin gallate, CID:107905; (−)-Epicatechin, CID:72276; (−)-Epigallocatechin gallate, CID: 65064; (−)-Epigallocatechin, CID: 72277; AAPH; ABTS; Catechin; Epicatechin; Epicatechin gallate; Epigallocatechin; Epigallocatechin gallate; Hemolysis; Hypochlorite.

MeSH terms

Antioxidants / chemistry*
Flavonols
Lipid Peroxidation
Polyphenols / chemistry*

Substances

Antioxidants
Flavonols
Polyphenols