Complications, length of stay, and cost of cholecystectomy in kidney transplant recipients

Am J Surg. 2018 Oct;216(4):694-698. doi: 10.1016/j.amjsurg.2018.07.023. Epub 2018 Jul 19.

Abstract

We hypothesized that cholecystectomy may be riskier for kidney transplant recipients (KTR) given their lifelong immunosuppression, physiologic impact of renal failure, and increased risk of gallstone and biliary disease. Using NIS, we compared mortality, morbidity, length of stay and cost in KTR vs non-KTR following cholecystectomy in the US from 2000 to 2011, adjusting for patient and hospital level factors, including transplant center status. Mortality was higher (OR 2.4), morbidity was higher (OR 1.3), LOS was longer (ratio 1.2), and costs were greater (ratio 1.1) for KTR compared to non-KTR following cholecystectomy. While it is clear that KTR are a high risk group following cholecystectomy, the cause of this increased risk requires further investigation.

Keywords: Cholecystectomy; General surgery; Kidney transplantation.

MeSH terms

  • Adult
  • Aged
  • Case-Control Studies
  • Cholecystectomy / economics*
  • Cholecystectomy / mortality
  • Cross-Sectional Studies
  • Databases, Factual
  • Female
  • Hospital Costs / statistics & numerical data*
  • Hospital Mortality
  • Humans
  • Kidney Transplantation*
  • Length of Stay / economics
  • Length of Stay / statistics & numerical data*
  • Linear Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Outcome Assessment, Health Care
  • Postoperative Complications / economics
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology*
  • Risk Factors
  • United States