A review of cutaneous leishmaniasis in Morocco: A vertical analysisto determine appropriate interventions for control and prevention

Acta Trop. 2018 Nov:187:275-283. doi: 10.1016/j.actatropica.2018.07.019. Epub 2018 Jul 26.

Abstract

Leishmaniasis is considered one of the most neglected diseases worldwide. In Morocco, cutaneous leishmaniasis is an important public health problem. Leishmania major and Leishmania tropica are the two major species in this country. Despite all efforts, monitoring and control of the cutaneous leishmaniasis is still challenging. We used for the first time a vertical analysis of the control of cutaneous leishmaniasis in Morocco from the document review and publications. This analysis allowed us to develop an epidemiological model that emphasized key possible interventions. No evaluation studies of these interventions in Morocco were done. Global Evidence underline the effectiveness of preventive interventions produced in integrate inter-sectorial strategy framework (e.g use of insecticide-treated bednets, indoor residual spraying and rodents' control) rather than treatments such as based thermotherapy, cryotherapy, photodynamic therapy, CO2 laser and paromomycin. Therefore, integrated vector management control (IVMC) with communityc participation is recommended as effective strategy. Strengthening of the IVMC with community involvement are necessary conditions to improve the program of cutaneous leishmaniasis and prevent epidemic foci appearance.

Keywords: Community participation; Cutaneous leishmaniasis; Integrated vector control management; Morocco; Vertical analysis.

Publication types

  • Review

MeSH terms

  • Animals
  • Antiprotozoal Agents / therapeutic use
  • Communicable Disease Control / methods
  • Community Participation
  • Cryotherapy
  • Humans
  • Hyperthermia, Induced
  • Incidence
  • Insect Control / methods*
  • Insect Vectors
  • Insecticide-Treated Bednets
  • Laser Therapy
  • Lasers, Gas
  • Leishmania major
  • Leishmania tropica
  • Leishmaniasis, Cutaneous / epidemiology*
  • Leishmaniasis, Cutaneous / prevention & control
  • Leishmaniasis, Cutaneous / therapy
  • Leishmaniasis, Cutaneous / transmission
  • Morocco / epidemiology
  • Paromomycin / therapeutic use
  • Photochemotherapy
  • Psychodidae / parasitology

Substances

  • Antiprotozoal Agents
  • Paromomycin