Prevention against malaria before the first antenatal visit and absence of anaemia at the first visit were protective from low birth weight: results from a South Kivu cohort, Democratic Republic of the Congo

Trans R Soc Trop Med Hyg. 2018 Aug 1;112(8):383-392. doi: 10.1093/trstmh/try066.

Abstract

Background: There is little information on the causes of low birth weight (LBW, <2500 g) in South Kivu. The authors determined the prevalence of LBW among full-term newborns, and its relationship with malaria and anaemia at the first antenatal visit (ANV1) in the rural health zone of Miti-Murhesa, in the eastern Democratic Republic of the Congo.

Methods: Four-hundred-and-seventy-eight pregnant women in the second trimester attending their first antenatal clinic were recruited between November 2010 and July 2011, and followed-up until delivery. Besides information on use of preventive measures and malaria morbidity, anthropometric measures and a blood sample were collected.

Results: Women's mean age (SD) at enrolment, was 26 (6.5) years (n=434); prevalence of malaria was 9.5% (43/453) and that of anaemia 32.2% (141/439). The latter was significantly more frequent in malaria-infected women and in those who had not been dewormed. At delivery, prevalence of LBW was 6.5% (23/355) and was independently associated with not sleeping under insecticide-treated bed net (p=0.030), mother's height <150 cm (p=0.001) and anaemia at the ANV1 (p=0.006).

Conclusion: In South Kivu, malaria and anaemia are important risk factors for LBW, and should be prevented among all women of reproductive age.

MeSH terms

  • Adolescent
  • Adult
  • Anemia / complications*
  • Anemia / epidemiology
  • Body Height
  • Cohort Studies
  • Democratic Republic of the Congo / epidemiology
  • Female
  • Fetal Growth Retardation / etiology
  • Fetal Growth Retardation / prevention & control*
  • Humans
  • Infant, Low Birth Weight / physiology*
  • Infant, Newborn
  • Malaria / complications*
  • Malaria / epidemiology
  • Malaria / prevention & control
  • Mosquito Nets
  • Pregnancy
  • Pregnancy Complications, Infectious* / epidemiology
  • Pregnancy Complications, Infectious* / prevention & control
  • Prenatal Care
  • Prevalence
  • Risk Factors
  • Young Adult