Successful treatment of a giant ovarian cyst by levothyroxin in a young adult woman: A case report

J Obstet Gynaecol Res. 2018 Nov;44(11):2115-2118. doi: 10.1111/jog.13755. Epub 2018 Jul 26.

Abstract

Ovarian cysts are one of the most common gynecologic affections for females. The most effective therapy is surgery, but not for all conditions. An 18-year-old woman was referred to our hospital because of menstruation disorder and abdominal distension. Ultrasound and computer tomography of the abdomen revealed a giant ovarian cyst. Magnetic resonance imaging revealed profound pituitary enlargement. Laboratory studies showed severe hypothyroidism, mild anemia, hyperlipidemia, hyperprolactinemia and an elevated level of cancer antigen-125. Regression of the giant ovarian cyst and pituitary enlargement was observed after a 5-month levothyroxine replacement therapy. Thus, for patients with ovarian cysts, hypothyroidism should be taken into account. Making correct diagnosis would avoid unnecessary surgery.

Keywords: giant ovarian cyst; hypothyroidism; pituitary enlargement.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Female
  • Humans
  • Hypothyroidism / drug therapy*
  • Ovarian Cysts / drug therapy*
  • Thyroxine / administration & dosage
  • Thyroxine / pharmacology*

Substances

  • Thyroxine