Role of Thromboelastography and Rotational Thromboelastometry in the Management of Cardiovascular Diseases

Clin Appl Thromb Hemost. 2018 Nov;24(8):1199-1207. doi: 10.1177/1076029618790092. Epub 2018 Jul 24.

Abstract

The monitoring of coagulation by viscoelastometric methods-thromboelastography and rotational thromboelastometry-may detect the contributions of cellular and plasma components of hemostasis. These methods might overcome some of the serious limitations of conventional laboratory tests. Viscoelastic testing can be repeatedly performed during and after surgery and thus provides a dynamic picture of the coagulation process during these periods. Several experiences with the use of these methods in cardiovascular surgery have been reported, but there is perspective for more frequent use of these assays in the assessment of platelet response to antiplatelet therapy and in the assessment of coagulation in patients on long-term dabigatran therapy. This article reviews the current role and future perspectives of thromboelastography and thromboelastometry in the management of cardiovascular diseases.

Keywords: anticoagulation; cardiovascular diseases; hemostasis; platelet function testing; thromboelastography and thromboelastometry.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / blood*
  • Cardiovascular Diseases / surgery*
  • Cardiovascular Surgical Procedures*
  • Humans
  • Thrombelastography / methods*