Highly efficient and precise base editing by engineered dCas9-guide tRNA adenosine deaminase in rats

Cell Discov. 2018 Jul 17:4:39. doi: 10.1038/s41421-018-0047-9. eCollection 2018.

Yuanwu Ma^{1

2}, Lei Yu¹, Xu Zhang¹, Changpeng Xin³, Shisheng Huang⁴, Lin Bai¹, Wei Chen¹, Ran Gao¹, Jing Li¹, Shuo Pan¹, Xiaolong Qi¹, Xingxu Huang⁴, Lianfeng Zhang^{1

2}

¹ 1Key Laboratory of Human Disease Comparative Medicine, NHFPC, Institute of Laboratory Animal Science, Peking Union Medicine College, Chinese Academy of Medical Sciences, Beijing, 100021 China.
² 2Neuroscience Center, Chinese Academy of Medical Sciences, Beijing, 100021 China.
³ 3Bio-Med Big Data Center Omics Core Facility, CAS-MPG Partner Institute of Computational Biology, Shanghai, 200031 China.
⁴ 4School of Life Science and Technology, Shanghai Tech University, Shanghai, 201210 China.

No abstract available