Azathioprine-induced myelosuppression in two pemphigus vulgaris patients with homozygous polymorphism of NUDT15

J Dermatol. 2019 Feb;46(2):e59-e61. doi: 10.1111/1346-8138.14542. Epub 2018 Jul 23.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Azathioprine / adverse effects*
  • Blood Cell Count
  • Coinfection / blood
  • Coinfection / drug therapy
  • Coinfection / immunology*
  • Coinfection / microbiology
  • Drug Therapy, Combination / methods
  • Female
  • Homozygote
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Myelopoiesis / drug effects*
  • Myelopoiesis / immunology
  • Pancytopenia / chemically induced
  • Pancytopenia / diagnosis
  • Pancytopenia / drug therapy
  • Pancytopenia / immunology
  • Pemphigus / drug therapy
  • Pemphigus / genetics
  • Polymorphism, Genetic
  • Pyrophosphatases / genetics*
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Immunosuppressive Agents
  • NUDT15 protein, human
  • Pyrophosphatases
  • Azathioprine