Quantitative pharmacology in antibody-drug conjugate development: armed antibodies or targeted small molecules?

Oncoscience. 2018 Jun 28;5(5-6):161-163. doi: 10.18632/oncoscience.435. eCollection 2018 May.

Authors

Ian Nessler¹, Eshita Khera¹, Greg M Thurber¹

Affiliation

¹ Department of Chemical Engineering, Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

No abstract available

Keywords: antibody-drug conjugate; immune cell recruitment; mechanism of action; payload delivery; receptor signaling.

Publication types

Editorial