The overarching objective of this research is to reduce the burden of 'alert fatigue' on patients and family caregivers who stay overnight in hospitals on units that provide continuous monitoring of cardiac and respiratory systems. When a patient develops respiratory compromise on the medical-surgical units of the hospital, the mortality rate is 29 times higher. Alarms require nurses to quickly respond, even when it is likely a false alarm. An anonymous survey was distributed to patients and family caregivers with 72 responses. Alarm sounds were judged most helpful to detect a high heart rate or unusual rhythm, and less helpful to detect a patient exiting from bed. The expectation was for an immediate response to an alarm, and that it would be annoying to have an alarm go off for hours. There was strong agreement with wanting alarm sounds to go to the nurse, but not be heard in the hospital room by patients or caregivers. Implications of these findings are discussed.