Bone cements for percutaneous vertebroplasty and balloon kyphoplasty: Current status and future developments

Zhiwei He; Qingpan Zhai; Muli Hu; Chengbin Cao; Jihui Wang; Huilin Yang; Bin Li

doi:10.1016/j.jot.2014.11.002

Bone cements for percutaneous vertebroplasty and balloon kyphoplasty: Current status and future developments

J Orthop Translat. 2014 Dec 12;3(1):1-11. doi: 10.1016/j.jot.2014.11.002. eCollection 2015 Jan.

Authors

Zhiwei He¹, Qingpan Zhai², Muli Hu², Chengbin Cao², Jihui Wang¹, Huilin Yang^{1

2}, Bin Li^{1

2}

Affiliations

¹ Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
² Orthopedic Institute, Soochow University, Suzhou, Jiangsu, China.

Abstract

Osteoporotic vertebral compression fractures (OVCFs) have gradually evolved into a serious health care problem globally. In order to reduce the morbidity of OVCF patients and improve their life quality, two minimally invasive surgery procedures, vertebroplasty (VP) and balloon kyphoplasty (BKP), have been developed. Both VP and BKP require the injection of bone cement into the vertebrae of patients to stabilize fractured vertebra. As such, bone cement as the filling material plays an essential role in the effectiveness of these treatments. In this review article, we summarize the bone cements that are currently available in the market and those still under development. Two major categories of bone cements, nondegradable acrylic bone cements (ABCs) and degradable calcium phosphate cements (CPCs), are introduced in detail. We also provide our perspectives on the future development of bone cements for VP and BKP.

Keywords: balloon kyphoplasty; bone cement; filling materials; osteoporotic vertebral compression fractures; vertebroplasty.

Publication types

Review