Diabetes mellitus and laboratory medicine in sub-Saharan Africa: challenges and perspectives

Acta Clin Belg. 2019 Jun;74(3):137-142. doi: 10.1080/17843286.2018.1498179. Epub 2018 Jul 20.

Abstract

Diabetes mellitus is an increasing public health problem in sub-Saharan Africa with a substantial socioeconomic burden. Although laboratory medicine has been recognized as one of the six key public health functions, there are still gaps in strengthening of laboratory services in developing countries. In the last decades, a lot of progress has been made in the diagnostic field of infectious diseases, whereas the diagnosis of noncommunicable diseases is still insufficient and uneven. This article analyses the challenges encountered in diagnosing and monitoring of diabetes mellitus in sub-Saharan Africa and explores new alternative diagnostic tools.

Keywords: Diabetes mellitus; glycated nail proteins; laboratory medicine; point-of-care testing; sub-Saharan Africa.

Publication types

  • Review

MeSH terms

  • Africa South of the Sahara / epidemiology
  • Clinical Laboratory Services / statistics & numerical data*
  • Clinical Laboratory Techniques
  • Developing Countries / statistics & numerical data
  • Diabetes Mellitus / diagnosis*
  • Diabetes Mellitus / epidemiology*
  • Fructosamine / analysis
  • Fructosamine / blood
  • Glycated Hemoglobin / analysis
  • Glycosuria / urine
  • Glycosylation
  • Humans
  • Monitoring, Physiologic
  • Nails / chemistry
  • Point-of-Care Testing
  • Poverty
  • Proteins / metabolism
  • Public Health / statistics & numerical data*

Substances

  • Glycated Hemoglobin A
  • Proteins
  • hemoglobin A1c protein, human
  • Fructosamine