Sensitive nonenzymatic detection of hydrogen peroxide at nitrogen-doped graphene supported-CoFe nanoparticles

Mehboob Hassan; Yue Jiang; Xiangjie Bo; Ming Zhou

doi:10.1016/j.talanta.2018.06.003

Sensitive nonenzymatic detection of hydrogen peroxide at nitrogen-doped graphene supported-CoFe nanoparticles

Talanta. 2018 Oct 1:188:339-348. doi: 10.1016/j.talanta.2018.06.003. Epub 2018 Jun 4.

Authors

Mehboob Hassan¹, Yue Jiang¹, Xiangjie Bo², Ming Zhou³

Affiliations

¹ Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Key Laboratory of Polyoxometalate Science of Ministry of Education, National & Local United Engineering Laboratory for Power Batteries, Department of Chemistry, Northeast Normal University, Changchun, Jilin Province 130024, P.R. China.
² Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Key Laboratory of Polyoxometalate Science of Ministry of Education, National & Local United Engineering Laboratory for Power Batteries, Department of Chemistry, Northeast Normal University, Changchun, Jilin Province 130024, P.R. China. Electronic address: baoxj133@nenu.edu.cn.
³ Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Key Laboratory of Polyoxometalate Science of Ministry of Education, National & Local United Engineering Laboratory for Power Batteries, Department of Chemistry, Northeast Normal University, Changchun, Jilin Province 130024, P.R. China. Electronic address: zhoum739@nenu.edu.cn.

PMID: 30029385
DOI: 10.1016/j.talanta.2018.06.003

Abstract

In this work, a new enzymeless sensor for hydrogen peroxide (H₂O₂) was constructed by supporting CoFe nanoparticles on the nitrogen-doped graphene (CoFe/NGR). In this preparation, the graphene oxide (GO) is first used as substrate for the growth of CoFe layered double hydroxides (CoFe LDHs) through hydrothermal reaction. Then, the pyrolysis of CoFe LDHs/GO under NH₃ produces CoFe/NGR. By supporting CoFe nanoparticles on NGR support, the electrocatalytic performance of CoFe is dramatically improved because of high electric conductivity of NGR. Consequently, the combination of CoFe and NGR allows the nonenzymatic detection of H₂O₂. Compared with the unsupported CoFe nanoparticles, the CoFe/NGR displays high electrocatalytic activity towards H₂O₂, enabling a high sensitivity of 435.7 μA mM^-1 cm^-2 and low detection limit of 0.28 μM towards the reduction of H₂O₂. Especially, the attractive feature of low cost and outstanding analytical performance of CoFe/NGR suggest it great potential in electrochemical sensor and biosensor fabrication.

Keywords: CoFe nanoparticles; Hydrogen peroxide; Layered double hydroxides; Nitrogen-doped graphene; Nonenzymatic sensor.