National short-term dietary exposure assessment of a selected group of pesticides in Argentina

J Environ Sci Health B. 2018;53(10):639-651. doi: 10.1080/03601234.2018.1474552. Epub 2018 Jul 19.

Abstract

An evaluation of acute dietary exposure to pesticide residues, applying deterministic and stochastic methods, was performed for a selected group of pesticides in two representative age groups from Argentina. Thus, 28 active ingredients (a.i.) and 75 food items were evaluated for the group of 2-5-year-old children, while 9 a.i. and 59 food items were considered for the 10-49-year-old women group. A deterministic assessment was conducting following the Food and Agriculture Organization (FAO) and World Health Organization (WHO) procedure but using the national maximum residue limits (MRLs) as pesticide residue concentration data, while in the stochastic approach, a theoretical distribution modeled with the available information was used. Food consumption data were obtained from the 2004-2005 comprehensive national nutrition and health survey. The risk was estimated by comparing the short-term dietary exposure with the acute reference dose (ARfD) values for each pesticide-food combination evaluated. In the deterministic assessment, 173 (39.1%) and 40 (31.3%) combinations exceeded the ARfD thresholds for the 2-5-year-old children and 10-49-year-old women groups, respectively. This conservative study generated relevant information as a first stage of acute dietary risk assessment in Argentina.

Keywords: ARfD; Acute risk assessment; dietary exposure; pesticide residue; stochastic modeling.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Agriculture
  • Argentina
  • Child
  • Child, Preschool
  • Dietary Exposure / adverse effects*
  • Dietary Exposure / statistics & numerical data
  • Environmental Exposure / statistics & numerical data
  • Environmental Monitoring / statistics & numerical data
  • Female
  • Food Analysis / statistics & numerical data*
  • Food Contamination / analysis*
  • Food Contamination / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Pesticide Residues / adverse effects*
  • Pesticide Residues / analysis*
  • Reference Values
  • Risk Assessment / methods*
  • Risk Assessment / statistics & numerical data
  • Young Adult

Substances

  • Pesticide Residues