Non-monoterpenoid azepinoindole alkaloids

Nat Prod Rep. 2018 Jul 19;35(12):1347-1382. doi: 10.1039/c8np00047f.

Abstract

Covering: 1969 to 2018 Azepinoindole natural products can be broadly classified as being of monoterpenoid or non-monoterpenoid origin. The non-monoterpenoid azepinoindoles have not received as much attention in the literature as their more revered monoterpenoid counterparts. In this review, an overview of all non-monoterpenoid azepinoindoles is provided. Various biological and chemical aspects are discussed, including their isolation, biosynthesis and the elegant total synthesis studies that have been inspired by these alkaloids.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Benzazepines / chemistry
  • Benzazepines / isolation & purification
  • Benzodioxoles / isolation & purification
  • Chemistry Techniques, Synthetic
  • Ergot Alkaloids / chemical synthesis
  • Indole Alkaloids / chemistry*
  • Indole Alkaloids / isolation & purification
  • Indole Alkaloids / metabolism*
  • Indole Alkaloids / pharmacology
  • Lignans / biosynthesis
  • Lignans / isolation & purification
  • Molecular Structure
  • Monoterpenes
  • Quinazolines / chemical synthesis
  • Quinazolines / chemistry
  • Quinazolines / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Benzazepines
  • Benzodioxoles
  • Ergot Alkaloids
  • Indole Alkaloids
  • Lignans
  • Monoterpenes
  • Quinazolines
  • aurantioclavine
  • cryptoheptine
  • hinckdentine A
  • fargesin