Prevalence and Clinical Profile of Human Salivirus in Children with Acute Gastroenteritis in Northern Italy, 2014-2015

Intervirology. 2018;61(1):49-52. doi: 10.1159/000490568. Epub 2018 Jul 18.

Abstract

Objective: Human Salivirus (SalV) has been associated with gastroenteritis on all continents.

Methods: This paper presents the real-time RT-PCR assay for the detection of SalV in clinical fecal samples collected from 192 hospitalized children with acute gastroenteritis in Piedmont, Italy.

Results: The most commonly detected virus was Norovirus genogroup II (GII) (33.8%), followed by Rotavirus (21.3%), Sapovirus (10.9%), Parechovirus (8%), Norovirus GI (6.7%), and Adenovirus (1%). PCR detected SalV in 1 (0.5%) subject.

Conclusions: Our data show that the detection rate of SalV in diarrheal children (0.5%) is lower than that observed in other countries, where it is reported in diarrheal children in 8.6-1.2% of patients.

Keywords: Coinfection; Gastroenteritis; RNA extraction; Real-time polymerase chain reaction; Salivirus.

MeSH terms

  • Acute Disease / epidemiology
  • Child
  • Child, Hospitalized
  • Child, Preschool
  • Diarrhea / epidemiology*
  • Diarrhea / virology
  • Feces / virology
  • Female
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / virology
  • Humans
  • Infant
  • Italy / epidemiology
  • Male
  • Picornaviridae / genetics
  • Picornaviridae / isolation & purification*
  • Picornaviridae Infections / epidemiology*
  • Picornaviridae Infections / virology
  • Prevalence