Laparoscopic Donor Hepatectomy for Adult Living Donor Liver Transplantation Recipients

Liver Transpl. 2018 Nov;24(11):1545-1553. doi: 10.1002/lt.25307.

Abstract

Even after 2 decades of experience in laparoscopic hepatectomy, data on purely laparoscopic approach for donor hepatectomy in adult living donor liver transplantation (LDLT) are limited. We report our initial experience of a purely laparoscopic approach for donor hepatectomy for adult recipients to explore its potential application in the management of donors. We did a retrospective data analysis of 54 consecutive patients operated on between May 2013 and February 2015. There were 41 right, 10 extended right, and 3 left hepatectomies. The median operative time was 436 minutes (range 294-684 minutes), and warm ischemia time was 6 minutes (2-12 minutes). Estimated blood loss was 300 mL (10-850 mL), and none of the patients required intraoperative transfusion. Four cases were converted to open laparotomy. The major complication rate was 16.7%, and biliary complication was the most frequent cause. Patients with normal anatomy had a major complication rate of 9.3% as compared with 45.5% in patients with anatomic variations. All patients recovered, and there was no mortality. In conclusion, a purely laparoscopic donor hepatectomy for adult LDLT recipients seems to be a feasible option; with careful patient selection and when performed by experienced surgeons, it may afford results comparable to the open method.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Anatomic Variation
  • End Stage Liver Disease / surgery
  • Feasibility Studies
  • Female
  • Hepatectomy / adverse effects
  • Hepatectomy / methods*
  • Humans
  • Laparoscopy / adverse effects
  • Laparoscopy / methods*
  • Liver / anatomy & histology
  • Liver / surgery
  • Liver Transplantation / methods
  • Living Donors*
  • Male
  • Middle Aged
  • Operative Time
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Tissue and Organ Harvesting / adverse effects
  • Tissue and Organ Harvesting / methods*
  • Transplant Donor Site / anatomy & histology
  • Transplant Donor Site / surgery
  • Treatment Outcome
  • Warm Ischemia / adverse effects
  • Young Adult