Cosmetics and ocular allergy

Curr Opin Allergy Clin Immunol. 2018 Oct;18(5):404-410. doi: 10.1097/ACI.0000000000000474.

Abstract

Purpose of review: The purpose of this review was to explore recent developments in the study of ocular cosmetics, as they pertain to adverse reactions that can be attributed to them.

Recent findings: Immunologically mediated adverse reactions to cosmetics are most commonly the result of sensitization to preservatives, fragrances and dyes used in these products. Metals such as nickel, cobalt, chromium and lead are used in products such as eye shadows and eye liners as well as toy makeup sets in amounts greater than the recommended amount of 1 ppm. Cosmetics make up the majority of fragrance-induced contact dermatitis. Recently, a free smartphone app was developed by American Contact Dermatitis Society that holds promise in better enabling patients to utilize their patch test data while shopping for cosmetics.

Summary: Both immediate and delayed hypersensitivity reactions linked to cosmetics are often the result of sensitization to preservatives, fragrances and additives in the products themselves. Despite significant advances in our understanding of these reactions, further research will be necessary to elucidate the mechanisms behind these reactions and bring this knowledge to the bedside as to improve patient care with potential cosmetic-based related allergic disorders.

MeSH terms

  • Allergens / adverse effects*
  • Coloring Agents / adverse effects*
  • Conjunctivitis, Allergic / chemically induced*
  • Cosmetics / adverse effects*
  • Cosmetics / chemistry
  • Dermatitis, Allergic Contact / etiology*
  • Humans
  • Hypersensitivity, Delayed / chemically induced*
  • Hypersensitivity, Immediate / chemically induced*
  • Metals / adverse effects
  • Mobile Applications
  • Odorants
  • Patch Tests
  • Preservatives, Pharmaceutical / adverse effects
  • Smartphone

Substances

  • Allergens
  • Coloring Agents
  • Cosmetics
  • Metals
  • Preservatives, Pharmaceutical