Abstract
We report new molecular evidence of locally acquired dengue virus infections in Ghana. We detected dengue viral RNA among children with suspected malaria by using a multipathogen real-time PCR. Subsequent sequence analysis revealed a close relationship with dengue virus serotype 2, which was implicated in a 2016 outbreak in Burkina Faso.
Keywords:
Accra; DNV2; Dengue; Ghana; Kintampo; Plasmodium; TaqMan array card; West Africa; assay; children; co-infected; endemic; febrile illness; malaria; malaria parasitemia; multi-pathogen; viruses.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Child
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Child, Preschool
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Coinfection
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Cross-Sectional Studies
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DNA, Protozoan / genetics*
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Dengue / epidemiology*
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Dengue / virology
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Dengue Virus / classification
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Dengue Virus / genetics*
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Dengue Virus / isolation & purification
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Female
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Ghana / epidemiology
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Humans
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Infant
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Infant, Newborn
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Malaria / epidemiology*
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Malaria / parasitology
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Male
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Plasmodium / classification
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Plasmodium / genetics*
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Plasmodium / isolation & purification
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RNA, Viral / genetics*
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Real-Time Polymerase Chain Reaction
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Serogroup
Substances
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DNA, Protozoan
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RNA, Viral