Novel lipid tools and probes for biological investigations

Aurélien Laguerre; Carsten Schultz

doi:10.1016/j.ceb.2018.06.013

Novel lipid tools and probes for biological investigations

Curr Opin Cell Biol. 2018 Aug:53:97-104. doi: 10.1016/j.ceb.2018.06.013. Epub 2018 Jul 14.

Authors

Aurélien Laguerre¹, Carsten Schultz²

Affiliations

¹ Dept. of Physiology & Pharmacology, Oregon Health and Science University (OHSU), Portland, OR, USA.
² Dept. of Physiology & Pharmacology, Oregon Health and Science University (OHSU), Portland, OR, USA; European Molecular Biology Laboratory (EMBL), Cell Biology and Biophysics Unit, 69117 Heidelberg, Germany. Electronic address: schulcar@ohsu.edu.

PMID: 30015291
DOI: 10.1016/j.ceb.2018.06.013

Abstract

We present the latest advances in lipid tool development for studying cellular membrane trafficking and metabolism. We focus on chemical modifications that are introduced to natural lipid structures. The new functionalities are used to follow and interfere with lipid dynamics in intact cells.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Cell Membrane / metabolism
Humans
Lipids / chemistry*
Molecular Imaging / methods*

Substances

Lipids